Ghyslain Mombo-Ngoma Selected Research

ferroquine

5/2021	A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria.
8/2017	Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria.
6/2012	Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections.
3/2011	Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.

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Ghyslain Mombo-Ngoma Research Topics

Disease

28	Malaria 11/2022 - 09/2007
13	Infections 01/2022 - 03/2011
10	Falciparum Malaria (Plasmodium falciparum Malaria) 02/2022 - 12/2011
2	Coinfection 01/2021 - 01/2014
2	Schistosomiasis (Bilharziasis) 01/2021 - 08/2015
2	Reinfection 01/2020 - 12/2019
2	Parasitic Diseases (Parasitic Disease) 10/2019 - 03/2013
1	Vomiting 05/2021
1	Communicable Diseases (Infectious Diseases) 05/2021
1	Tuberculosis (Tuberculoses) 05/2021
1	Growth Disorders 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Scabies (Sarcoptic Mange) 01/2020
1	Parasitemia 11/2019
1	Fever (Fevers) 01/2018

Drug/Important Bio-Agent (IBA)

9	Pharmaceutical PreparationsIBA 02/2022 - 03/2011
9	pyrimethamine drug combination fanasil (Fansidar)FDA Link 11/2021 - 09/2007
7	Antimalarials (Antimalarial Agents)IBA 02/2022 - 03/2011
6	artemisinin (artemisinine)IBA 02/2022 - 10/2011
5	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2020 - 07/2012
5	Mefloquine (Lariam)FDA LinkGeneric 01/2019 - 10/2010
4	ferroquineIBA 05/2021 - 03/2011
3	piperaquineIBA 11/2021 - 10/2017
3	artefenomelIBA 05/2021 - 10/2017
3	AntigensIBA 01/2021 - 01/2014
3	Amodiaquine (Camoquin)FDA Link 01/2020 - 08/2017
3	ArtesunateIBA 01/2020 - 08/2017
2	artesunate drug combination pyronaridine tetraphosphateIBA 01/2022 - 01/2021
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 11/2021 - 01/2015
2	VaccinesIBA 05/2021 - 01/2021
2	1- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA 01/2021 - 01/2020
2	Immunoglobulin G (IgG)IBA 01/2021 - 10/2019
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 11/2015
1	Cell Adhesion MoleculesIBA 11/2022
1	Hyaluronic Acid (Hyaluronan)IBA 11/2022
1	Conditioned Culture MediaIBA 11/2022
1	Drug CombinationsIBA 02/2022
1	artenimol (dihydroartemisinin)IBA 11/2021
1	Methylene Blue (Methylthioninium Chloride)FDA Link 01/2021
1	Transaminases (Aminotransferases)IBA 01/2021
1	Rabies Vaccines (Rabies Vaccine)FDA Link 01/2021
1	Recombinant ProteinsIBA 01/2021
1	Aluminum Hydroxide (Algeldrate)FDA Link 01/2021
1	TabletsIBA 01/2021
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2021
1	TetracyclinesIBA 01/2021
1	eravacyclineIBA 01/2021
1	OF 743IBA 01/2021
1	pyronaridineIBA 01/2021
1	Malaria VaccinesIBA 01/2021
1	NITD 609IBA 07/2020
1	benzyl benzoate (Ansar)FDA Link 01/2020
1	Recombinases (Recombinase)IBA 01/2020
1	Nucleic AcidsIBA 01/2020
1	Merozoite Surface Protein 1 (MSA1)IBA 12/2019
1	Indicators and Reagents (Reagents)IBA 11/2019
1	DNA (Deoxyribonucleic Acid)IBA 10/2019
1	Chloroquine (Aralen)FDA LinkGeneric 10/2019
1	Peptides (Polypeptides)IBA 10/2019
1	ganaplacideIBA 10/2018
1	fosmidomycinIBA 01/2018
1	A-Form DNA (A-DNA)IBA 01/2018
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2018
1	Single-Stranded DNA (DNA, Single Stranded)IBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	18S Ribosomal RNAIBA 10/2017
1	AntibodiesIBA 01/2017
1	Praziquantel (Biltricide)FDA Link 08/2015
1	CytokinesIBA 08/2015
1	4-aminoquinolineIBA 06/2012
1	Azithromycin (Zithromax)FDA LinkGeneric 10/2010

Therapy/Procedure

9	Therapeutics 02/2022 - 10/2011
2	Chemoprevention 01/2020 - 11/2013
2	Aftercare (After-Treatment) 01/2020 - 08/2015
1	Fluid Therapy (Oral Rehydration Therapy) 02/2022
1	Contraindications 01/2021
1	Prenatal Care (Care, Prenatal) 11/2013